Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15761339 | 0.81 | APP (0.61) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL2303318 | 0.78 | APP (0.50) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL11128958 | 0.78 | APP (0.50) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL12533565 | 0.75 | APP (0.55) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL20945390 | 0.74 | MAOB (0.54) | APPLMNACYP1A2PTGS1SLC6A2 | |
| Benzylphenylether SCHEMBL61660 | 0.74 | LMNA (0.74) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL850999 | 0.74 | APP (0.78) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL5441069 | 0.74 | MAOB (0.66) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL15761346 | 0.74 | LMNA (0.61) | APPLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL4796227 | 0.73 | NPC1 (0.60) | APPCYP2C19MAOBMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4957933-A | Fungicidal oxazolidinones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-18 | — | — | US | disclosed |