Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811345 | 1.00 | ITGB1 (0.34) | ITGB1ITGA5ITGA4THRB | |
| SCHEMBL10416098 | 1.00 | ITGB1 (0.34) | ITGB1ITGA5ITGA4THRB | |
| SCHEMBL31436154 | 0.87 | PTGER3 (0.32) | — | |
| SCHEMBL9811315 | 0.83 | BRD4 (0.32) | — | |
| SCHEMBL6078873 | 0.78 | BAZ2B (0.33) | — | |
| SCHEMBL6078880 | 0.78 | BAZ2B (0.33) | — | |
| SCHEMBL7459267 | 0.78 | BAZ2B (0.33) | — | |
| SCHEMBL9811361 | 0.77 | — | — | |
| SCHEMBL8644358 | 0.77 | — | — | |
| SCHEMBL8644356 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918184-A | REACTING 1,3-THIAZOLIDINE-2-THIONE DERIVATIVE WITH TIN TRIFLUOROMETHANESULFONATE TO FORM ENOLATE, REACTING WITH SUBSTITUTED AZETIDINONE | LEDERLE (JAPAN), LTD. (JP) | 1990-04-17 | — | — | US | disclosed |