SCHEMBL9811315

SCHEMBL9811315

C[C@@H](O[Si](C)(C)C(C)(C)C)N1C(=O)C[C@H]1CCO

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31436154 0.86 PTGER3 (0.32)
SCHEMBL9811345 0.83 ITGB1 (0.34)
SCHEMBL10415296 0.83 ITGB1 (0.34)
SCHEMBL10416098 0.83 ITGB1 (0.34)
SCHEMBL9811529 0.78
SCHEMBL8700779 0.75 THRB (0.32) BRD4
SCHEMBL8784545 0.73 MAPT (0.31)
SCHEMBL8697639 0.73 MAPT (0.31)
SCHEMBL9811361 0.73
SCHEMBL8694211 0.73 MAPT (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0223588-B1 PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-12 EP disclosed