Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416002 | 1.00 | CA1 (0.45) | CA1CA2NFKB1CA4CCNC | |
| SCHEMBL690926 | 0.76 | CYP2A6 (0.41) | CA1CA2HTTKDM4ESMN1; SMN2 | |
| SCHEMBL19216677 | 0.75 | MEN1 (0.50) | CA1CA2NFKB1CA4CCNC | |
| SCHEMBL2137394 | 0.74 | L3MBTL1 (0.46) | CA1CA2HTTKDM4ELMNA | |
| SCHEMBL2137392 | 0.74 | L3MBTL1 (0.46) | CA1CA2HTTKDM4ELMNA | |
| SCHEMBL18029054 | 0.73 | ALDH1A1 (0.33) | CMA1ALDH1A1 | |
| SCHEMBL8746633 | 0.72 | CA1 (0.57) | CA1CA2NFKB1CA4HTT | |
| SCHEMBL932002 | 0.71 | NR4A1 (0.46) | KDM4ECMA1ALDH1A1 | |
| SCHEMBL79668 | 0.69 | HDAC8 (0.67) | CA1CA2NFKB1CA4HTT | |
| SCHEMBL2903467 | 0.69 | HDAC8 (0.67) | CA1CA2NFKB1CA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4948796-A | TREATING CEREBO-VASCULARE DISEASES | TOYAMA CHEMICAL CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |