Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10678087 | 0.83 | MEN1 (0.45) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10832880 | 0.83 | MAPT (0.40) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10831791 | 0.82 | MAPT (0.41) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10678486 | 0.82 | MEN1 (0.42) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10839195 | 0.82 | MEN1 (0.42) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL11291351 | 0.81 | MEN1 (0.41) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10699884 | 0.81 | LMNA (0.43) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10838601 | 0.81 | MEN1 (0.44) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10695608 | 0.80 | MEN1 (0.46) | MEN1KMT2ACCKBRMAPTPDE3A | |
| SCHEMBL10755934 | 0.79 | MEN1 (0.41) | MEN1KMT2ACCKBRMAPTPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939253-A | 2-oxoazetidin-1-yloxy acetic acids and analogs | E. R. SQUIBB & SONS, INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4794108-A | BACTERICIDES, MICROBIOCIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0135194-A1 | Azetidinones and their production | Takeda Chemical Industries, Ltd. (JP) | 1985-03-27 | — | — | EP | disclosed |