Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319068 | 0.89 | KMT2A (0.68) | SIGMAR1KMT2AMEN1MC4RCYP1A2 | |
| SCHEMBL25802372 | 0.84 | SIGMAR1 (0.58) | SIGMAR1MC4RLMNADRD4POLB | |
| SCHEMBL2395111 | 0.75 | RECQL (0.62) | SIGMAR1KMT2AMEN1DRD4ACHE | |
| SCHEMBL10256869 | 0.74 | SLC6A3 (0.63) | SIGMAR1KMT2AMEN1CYP1A2ACHE | |
| SCHEMBL25537483 | 0.73 | KMT2A (0.73) | KMT2AMEN1CYP1A2CYP2C19LMNA | |
| SCHEMBL1264072 | 0.73 | RECQL (0.52) | CYP1A2CYP2C19DRD4ACHE | |
| SCHEMBL1041303 | 0.73 | SIGMAR1 (1.00) | SIGMAR1KMT2AMC4RLMNADRD4 | |
| SCHEMBL1415730 | 0.73 | SIGMAR1 (1.00) | SIGMAR1KMT2AMC4RLMNADRD4 | |
| SCHEMBL2489199 | 0.73 | SIGMAR1 (1.00) | SIGMAR1KMT2AMC4RLMNADRD4 | |
| SCHEMBL8188324 | 0.73 | SIGMAR1 (1.00) | SIGMAR1KMT2AMC4RLMNADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4937252-A | 2-thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-06-26 | — | — | US | disclosed |