SCHEMBL10416670

SCHEMBL10416670

CC(=O)C(N)(C(C)=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
USP2 O75604 1/20 0.45
SLCO1B1 Q9Y6L6 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
PDE4A P27815 1/20 0.43
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2227602 0.86 USP2 (0.44) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL1524925 0.82 USP2 (0.37) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL9641502 0.82 USP2 (0.37) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL4861016 0.82 LMNA (0.37) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL29020598 0.79 LMNA (0.46) LMNAL3MBTL1USP2SLCO1B1TDP1
SCHEMBL4726851 0.78 USP2 (0.39) LMNAL3MBTL1USP2SLCO1B1TDP1
Mannitol SCHEMBL29235000 0.77 LMNA (0.61) LMNAL3MBTL1USP2SLCO1B1TDP1
Mannitol SCHEMBL3017327 0.77 LMNA (0.69) LMNAL3MBTL1USP2SLCO1B1TDP1
Mannitol SCHEMBL11031577 0.77 LMNA (0.69) LMNAL3MBTL1USP2SLCO1B1TDP1
Mannitol SCHEMBL7927609 0.77 LMNA (0.69) LMNAL3MBTL1USP2SLCO1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4978395-A POLYEPOXIDES AND POLYLACTONES OF DERIVATIVES OF RESIN ACIDS OR TALL OIL; DISPERSANTS IN BOTH POLAR AND NONPOLAR DILUENTS; INKS; PAINTS CANESTRI GIUSEPPE (IT) 1990-12-18 US disclosed
EP-0332237-A1 Polymeric dispersing agent Canestri, Giuseppe (IT) 1989-09-13 EP disclosed