SCHEMBL4861016

SCHEMBL4861016

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nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4828105 0.91 LMNA (0.34) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL2227602 0.85 USP2 (0.44) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL4744788 0.83 USP2 (0.38) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL3624773 0.83 USP2 (0.38) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL2719053 0.83 USP2 (0.38) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL10416670 0.82 LMNA (0.46) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL9641502 0.81 USP2 (0.37) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL1524925 0.81 USP2 (0.37) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL27539360 0.78 LMNA (0.36) LMNAUSP2SLCO1B1L3MBTL1PDE4A
SCHEMBL29250363 0.77 USP2 (0.34) LMNAUSP2SLCO1B1L3MBTL1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402575-B2 Methods of treating inflammation MANITOBA, UNIVERSITY OF (CA) 2008-07-22 US claimed
US-20040214792-A1 Methods of treating inflammation MANITOBA, UNIVERSITY OF (CA) 2004-10-28 US claimed
CN-107522779-B Polypeptide having sugar chain attached thereto and pharmaceutical composition containing the same 株式会社糖锁工学研究所 2021-10-26 CN disclosed
CN-106146649-B Polypeptide having sugar chain attached thereto and pharmaceutical composition containing the same 株式会社糖锁工学研究所 2020-09-01 CN disclosed
US-7402575-B2 Methods of treating inflammation MANITOBA, UNIVERSITY OF (CA) 2008-07-22 US disclosed
US-20040214792-A1 Methods of treating inflammation MANITOBA, UNIVERSITY OF (CA) 2004-10-28 US disclosed