Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9457904 | 0.89 | MAOB (0.59) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL9457910 | 0.89 | MAOB (0.59) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL8450091 | 0.77 | MAOB (0.53) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL8450086 | 0.77 | MAOB (0.53) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL9971655 | 0.76 | HDAC2 (0.58) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL10417333 | 0.72 | MAPT (0.43) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL8454093 | 0.72 | MAOB (0.58) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL6011001 | 0.71 | MAOB (0.57) | MAOBHDAC2FBP1ALDH1A1MAPT | |
| SCHEMBL15964288 | 0.71 | MAOB (0.64) | MAOB | |
| SCHEMBL29260529 | 0.70 | MAOB (0.56) | MAOBHDAC2FBP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4980486-A | Phenyl isothiocyanates | HOFFMANN-LA ROCHE INC. (US) | 1990-12-25 | — | — | US | disclosed |