Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10417444 | 0.90 | PTPN1 (0.56) | PTPN1ATMCD274CA1CA2 | |
| SCHEMBL30863678 | 0.83 | TLR2 (0.55) | PTPN1 | |
| SCHEMBL10417441 | 0.83 | CD274 (0.42) | PTPN1CD274 | |
| SCHEMBL13324010 | 0.78 | SIRT2 (0.61) | SIRT2SIRT1FOLH1CAPN1CAPN2 | |
| SCHEMBL24238520 | 0.77 | FOLH1 (0.64) | SIRT2SIRT1FOLH1 | |
| SCHEMBL9698236 | 0.77 | FOLH1 (0.64) | SIRT2SIRT1FOLH1 | |
| SCHEMBL9697060 | 0.77 | FOLH1 (0.64) | SIRT2SIRT1FOLH1 | |
| SCHEMBL19307785 | 0.77 | FOLH1 (0.64) | SIRT2SIRT1FOLH1 | |
| SCHEMBL19925534 | 0.77 | FOLH1 (0.64) | SIRT2SIRT1FOLH1 | |
| SCHEMBL6950440 | 0.77 | FOLH1 (0.64) | SIRT2SIRT1FOLH1CAPN1CAPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4935536-A | TRIALKOXYBENZYL PROTECTED AMINO ACID | MILLIPORE CORPORATION (US) | 1990-06-19 | — | — | US | disclosed |