Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640224 | 1.00 | HCAR2 (0.62) | HCAR2ALDH1A1TSHRL3MBTL1KDM4E | |
| SCHEMBL10894107 | 0.96 | HCAR2 (0.57) | HCAR2ALDH1A1TSHRL3MBTL1KDM4E | |
| SCHEMBL10942733 | 0.88 | ALDH1A1 (0.53) | HCAR2ALDH1A1TSHRL3MBTL1KDM4E | |
| SCHEMBL9331315 | 0.86 | TSHR (0.54) | HCAR2ALDH1A1TSHRL3MBTL1KDM4E | |
| SCHEMBL3302489 | 0.85 | ALDH1A1 (0.69) | ALDH1A1TSHRL3MBTL1KDM4ETDP1 | |
| SCHEMBL28492073 | 0.83 | ALDH1A1 (0.67) | ALDH1A1TSHRL3MBTL1KDM4ETDP1 | |
| SCHEMBL30198617 | 0.83 | THRB (0.59) | ALDH1A1TSHRL3MBTL1KDM4ETDP1 | |
| SCHEMBL67527 | 0.83 | THRB (0.59) | ALDH1A1TSHRL3MBTL1KDM4ETDP1 | |
| SCHEMBL8944715 | 0.81 | ALDH1A1 (0.47) | HCAR2ALDH1A1TSHRL3MBTL1KDM4E | |
| Phthalic Acid SCHEMBL11481694 | 0.81 | HCAR2 (0.67) | HCAR2ALDH1A1TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925904-A | GELATION INHIBITION WITH PHENOTHIAZINE; SHELF LIFE | HILTI AKTIENGESELLSCHAFT (LI) | 1990-05-15 | — | — | US | disclosed |