Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | PRNP | P04156 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinazolinone SCHEMBL7746268 | 0.98 | PARP1 (0.47) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Quinazolinone SCHEMBL8201415 | 0.98 | PARP1 (0.47) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Quinazolinone SCHEMBL7744396 | 0.96 | PARP1 (0.46) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Quinazolinone SCHEMBL5266556 | 0.88 | ALDH1A1 (0.42) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL29258736 | 0.76 | PDE3B (0.44) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL30882780 | 0.76 | PDE3B (0.44) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL1193984 | 0.74 | ALDH1A1 (0.59) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| 4-Aminoquinazoline SCHEMBL5334497 | 0.74 | ALDH1A1 (0.43) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL3402056 | 0.74 | KDM4C (0.49) | PARP1MAPTCHEK1 | |
| SCHEMBL8622177 | 0.74 | ACVR1 (0.46) | PARP1SMN1; SMN2PDPK1CA12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 17568 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121226265-B | Acylhydrazone compound containing quinazolinone fragment, and preparation method and application thereof | BOZHOU UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122059885-A | Process for preparing quinazolinone derivatives | 宁夏医科大学 | 2026-05-19 | — | — | CN | claimed |
| US-12629683-B2 | Oligonucleotide encoded chemical libraries | Plexium, Inc. (US) | 2026-05-19 | — | — | US | claimed |
| CN-122010957-A | Preparation method of fullerene pyrrolidine quinazolinone | 湖北大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4263518-B1 | NEW QUINAZOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2026-04-01 | — | — | EP | claimed |
| EP-4695308-A1 | ENGINEERED ANTIBODIES AND USES THEREOF | Invitrogen BioServices India Private Limited (IN) | 2026-02-18 | — | — | EP | claimed |
| EP-4653437-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Innovo Therapeutics Inc. (KR) | 2025-11-26 | — | — | EP | claimed |
| US-12465559-B2 | Fluorescent curable dental composition and cured product thereof | KURARAY NORITAKE DENTAL INC. (JP) | 2025-11-11 | — | — | US | claimed |
| US-20250325022-A1 | AEROSOL GENERATING SYSTEM, OPERATING METHOD THEREOF, AND AEROSOL GENERATING ARTICLE THEREFOR | KT&G CORPORATION (KR) | 2025-10-23 | — | — | US | claimed |
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | claimed |
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | claimed |
| US-4183931-A | SEDATIVE-HYPNOTICS, ANTICONVULSANTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS | RESEARCH CORPORATION (US) | 1980-01-15 | — | — | US | claimed |
| WO-1980000040-A1 | ORGANIC HALOGEN COMPOUNDS USED IN DIRECT POSITIVE EMULSIONS | DU PONT (US) | 1980-01-10 | — | — | WO | claimed |
| US-4113637-A | DISPERSANTS, DETERGENTS | INSTITUT FRANCAIS DU PETROLE (FR) | 1978-09-12 | — | — | US | claimed |
| US-4099002-A | QUINAZOLINONE DERIVATIVES AND A PROCESS FOR PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-07-04 | — | — | US | claimed |
| US-4067868-A | Production of quinazolinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-10 | — | — | US | claimed |
| US-4054658-A | SEDATIVES, HYPNOSIS | WILLIAM H. RORER, INC. (US) | 1977-10-18 | — | — | US | claimed |
| US-3980645-A | Fused quinazolinones and a process for production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-09-14 | — | — | US | claimed |
| US-3970654-A | Antiviral 2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-07-20 | — | — | US | claimed |
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | claimed |