Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 4/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.45 |
| ▸ | PGR | P06401 | 6/20 | 0.45 |
| ▸ | AR | P10275 | 6/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619163 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL8192700 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL8207710 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL3083179 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL7565596 | 1.00 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2HIF1A | |
| Methyl Alcohol SCHEMBL9756756 | 0.99 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL8470202 | 0.93 | NFKB1 (0.46) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL8470203 | 0.93 | NFKB1 (0.46) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL2556587 | 0.90 | NFKB1 (0.56) | NFKB1NFKB2RELAKCNH2HIF1A | |
| SCHEMBL8203795 | 0.89 | NFKB1 (0.44) | NFKB1NFKB2RELAKCNH2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4975537-A | Δ9(11) -angiostatic steroids | THE UPJOHN COMPANY (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0221705-A1 | Tetrahydro angiostatic steroids | THE UPJOHN COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |
| WO-1987002672-A1 | TETRAHYDRO ANGIOSTATIC STEROIDS | THE UPJOHN COMPANY (US) | 1987-05-07 | — | — | WO | disclosed |