Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 6/20 | 0.39 |
| ▸ | PGR | P06401 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470202 | 1.00 | NFKB1 (0.46) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL7565596 | 0.93 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL3083179 | 0.93 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL8192700 | 0.93 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL9619163 | 0.93 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL8207710 | 0.93 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL10419014 | 0.93 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| Methyl Alcohol SCHEMBL9756756 | 0.92 | NFKB1 (0.54) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL8203795 | 0.89 | NFKB1 (0.44) | NFKB1NFKB2RELAKCNH2FNTA | |
| SCHEMBL9627248 | 0.89 | ALDH1A1 (0.50) | NFKB1NFKB2RELAKCNH2FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019731-A1 | STEROIDS WHICH INHIBIT ANGIOGENESIS | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | claimed |
| US-5972922-A | Steroids which inhibit angiogenesis | ALCON LABORATORIES, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1991019731-A1 | STEROIDS WHICH INHIBIT ANGIOGENESIS | THE UPJOHN COMPANY (US) | 1991-12-26 | — | — | WO | disclosed |