Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419972 | 0.95 | PPARA (0.44) | PPARAPPARGEPHX2MAPTALDH1A1 | |
| SCHEMBL10420226 | 0.95 | PPARA (0.44) | PPARAPPARGEPHX2MAPTALDH1A1 | |
| SCHEMBL11357277 | 0.92 | ALDH1A1 (0.42) | PPARAPPARGEPHX2MAPTALDH1A1 | |
| SCHEMBL9039166 | 0.83 | CYP4A11 (0.52) | MAPTALDH1A1KDM4ELMNAALOX12 | |
| SCHEMBL11348091 | 0.83 | EPHX2 (0.48) | PPARAPPARGEPHX2MAPTALDH1A1 | |
| SCHEMBL11038591 | 0.81 | PPARA (0.51) | PPARAPPARGEPHX2MAPTALDH1A1 | |
| SCHEMBL9343047 | 0.80 | CYP4A11 (0.53) | MAPTALDH1A1KDM4ELMNAALOX12 | |
| SCHEMBL15445639 | 0.79 | CYP1A2 (0.41) | MAPTALDH1A1LMNAALOX12CYP1A2 | |
| SCHEMBL11205164 | 0.79 | PPARA (0.56) | PPARAPPARGEPHX2MAPTALDH1A1 | |
| SCHEMBL9343689 | 0.79 | CYP4A11 (0.52) | MAPTALDH1A1KDM4ELMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |