Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941427 | 0.90 | MDM2 (0.56) | MDM2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10941159 | 0.90 | MDM2 (0.56) | MDM2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL10941212 | 0.90 | MDM2 (0.56) | MDM2HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL11208077 | 0.86 | PPARA (0.56) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL20569893 | 0.85 | PPARA (0.58) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10419238 | 0.81 | PPARA (0.51) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL11312936 | 0.80 | PPARA (0.64) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10419244 | 0.80 | CNR1 (0.50) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10419234 | 0.79 | PPARA (0.57) | PPARAPPARGPDPK1PLAAT3PLAAT5 | |
| SCHEMBL10419412 | 0.79 | ALB (0.56) | PPARAPPARGHDAC1SCN5ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |