Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.64 |
| ▸ | PPARG | P37231 | 5/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20569893 | 0.94 | PPARA (0.58) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL11208077 | 0.93 | PPARA (0.56) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL7828484 | 0.90 | PPARG (0.50) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL11205164 | 0.84 | PPARA (0.56) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL5079189 | 0.84 | PPARA (0.59) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL5079192 | 0.84 | PPARA (0.59) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL10419238 | 0.83 | PPARA (0.51) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL3544881 | 0.82 | GRIK1 (0.59) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL13061661 | 0.81 | ALDH1A1 (0.48) | PPARAPPARGHSD17B10 | |
| SCHEMBL3544544 | 0.81 | MAOB (0.53) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038343-A1 | SUBSTITUTED CARBOXYLIC CETO-ACIDS, PROCESS FOR THE PREPARATION THEREOF, USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM. | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-10-28 | — | — | EP | disclosed |
| WO-1981001285-A1 | SUBSTITUTED CARBOXYLIC CETO-ACIDS,PROCESS FOR THE PREPARATION THEREOF,USE THEREOF AND MEDICINAL COMPOSITIONS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-05-14 | — | — | WO | disclosed |