Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | GJB2 | P29033 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12703682 | 1.00 | LMNA (0.39) | LMNAALDH1A1CYP2D6MAPK1LGALS8 | |
| SCHEMBL5026256 | 0.92 | SLC6A2 (0.40) | LMNAALDH1A1CYP2D6LGALS8NT5E | |
| SCHEMBL12703731 | 0.91 | PDPK1 (0.41) | LMNAALDH1A1CYP2D6MAPK1NT5E | |
| SCHEMBL1044185 | 0.91 | PDPK1 (0.41) | LMNAALDH1A1CYP2D6MAPK1NT5E | |
| SCHEMBL12704017 | 0.88 | ALDH1A1 (0.38) | LMNAALDH1A1LGALS8PDPK1MTOR | |
| SCHEMBL12703699 | 0.87 | LMNA (0.41) | LMNAALDH1A1CYP2D6MAPK1LGALS8 | |
| SCHEMBL5127160 | 0.87 | LMNA (0.41) | LMNAALDH1A1CYP2D6MAPK1LGALS8 | |
| SCHEMBL12703842 | 0.84 | LMNA (0.36) | LMNAALDH1A1CYP2D6MAPK1LGALS8 | |
| SCHEMBL12703968 | 0.84 | LMNA (0.36) | LMNAALDH1A1CYP2D6MAPK1LGALS8 | |
| SCHEMBL12703760 | 0.84 | CA12 (0.41) | LMNAALDH1A1LGALS9PDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919599-B2 | Production of L-iduronate containing polysaccharides | THE UNIVERSITY OF MANCHESTER (GB) | 2011-04-05 | — | — | US | claimed |
| EP-2272855-A2 | Production of l-iduronate containing polysaccharides | The University Of Manchester (GB) | 2011-01-12 | — | — | EP | claimed |
| US-20090137792-A1 | Production Of L-Iduronate Containing Polysaccharides | THE UNIVERSITY OF MANCHESTER (GB) | 2009-05-28 | — | — | US | claimed |
| EP-1885736-A1 | PRODUCTION OF L-IDURONATE CONTAINING POLYSACCHARIDES | The University of Manchester (GB) | 2008-02-13 | — | — | EP | claimed |
| WO-2006129075-A1 | PRODUCTION OF L-IDURONATE CONTAINING POLYSACCHARIDES | THE UNIVERSITY OF MANCHESTER (GB) | 2006-12-07 | — | — | WO | claimed |
| US-7919599-B2 | Production of L-iduronate containing polysaccharides | THE UNIVERSITY OF MANCHESTER (GB) | 2011-04-05 | — | — | US | disclosed |
| EP-2272855-A2 | Production of l-iduronate containing polysaccharides | The University Of Manchester (GB) | 2011-01-12 | — | — | EP | disclosed |
| US-20090137792-A1 | Production Of L-Iduronate Containing Polysaccharides | THE UNIVERSITY OF MANCHESTER (GB) | 2009-05-28 | — | — | US | disclosed |
| EP-1885736-A1 | PRODUCTION OF L-IDURONATE CONTAINING POLYSACCHARIDES | The University of Manchester (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006129075-A1 | PRODUCTION OF L-IDURONATE CONTAINING POLYSACCHARIDES | THE UNIVERSITY OF MANCHESTER (GB) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137792-A1 | Production Of L-Iduronate Containing Polysaccharides | IDUA, DDOST, CSGALNACT1 | LMNA 1166/4885ALDH1A1 3504/4885CYP2D6 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.