Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10418815 | 0.84 | CYP2C9 (0.49) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9613997 | 0.82 | PPARA (0.50) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10419191 | 0.82 | PPARG (0.47) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9614100 | 0.82 | PPARA (0.50) | PPARAPPARGPLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10419188 | 0.81 | PPARG (0.52) | PPARAPPARGKCNH2HSD17B10 | |
| SCHEMBL9695329 | 0.81 | PPARG (0.52) | PPARAPPARGKCNH2HSD17B10 | |
| SCHEMBL9696793 | 0.81 | PPARA (0.43) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL11208077 | 0.81 | PPARA (0.56) | PPARAPPARGHDAC3HDAC4HDAC1 | |
| SCHEMBL9613992 | 0.80 | PPARA (0.44) | PPARAPPARGHSD17B10 | |
| SCHEMBL9614128 | 0.79 | PPARG (0.43) | PPARAPPARGPLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |