Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.44 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614003 | 0.82 | PPARG (0.50) | PPARAPPARGHSD17B10CYP2C19CYP2C9 | |
| SCHEMBL9614063 | 0.80 | PPARA (0.47) | PPARAPPARGCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL10420481 | 0.80 | PPARA (0.49) | PPARAPPARGHSD17B10 | |
| SCHEMBL9613870 | 0.79 | PPARA (0.51) | PPARAPPARG | |
| SCHEMBL9613989 | 0.77 | PPARA (0.43) | PPARAPPARGHSD17B10EDNRBEDNRA | |
| SCHEMBL9613951 | 0.73 | PPARA (0.67) | PPARAPPARG | |
| SCHEMBL11228865 | 0.73 | TAAR1 (0.54) | — | |
| SCHEMBL3584933 | 0.72 | FFAR1 (0.51) | PPARAPPARG | |
| SCHEMBL9614080 | 0.72 | PPARA (0.55) | PPARAPPARGKDM4E | |
| SCHEMBL9613841 | 0.71 | PPARG (0.43) | PPARAPPARGRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145611-A | Diabetes | BOEHRINGER MANNHEIM GMBH (DE) | 1992-09-08 | — | — | US | disclosed |