SCHEMBL104205

SCHEMBL104205

BB.CC(C)(O)C(C)(C)O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3890189 1.00 THRB (0.46) THRBALDH1A1TSHR
SCHEMBL504018 0.88 THRB (0.55) THRBALDH1A1TSHR
SCHEMBL8968 0.88
SCHEMBL27028519 0.88 THRB (0.55) THRBALDH1A1TSHR
SCHEMBL16291745 0.84 THRB (0.54) THRBALDH1A1TSHR
SCHEMBL789340 0.82
SCHEMBL129302 0.82
Ammonia Solution, Strong SCHEMBL8694521 0.82
SCHEMBL21494164 0.82 THRB (0.50) THRBALDH1A1TSHR
Hydrochloric Acid SCHEMBL7537660 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 684 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119119043-A Synthesis method of 4,4' - (1, 10-phenanthroline-4, 7-diyl) sodium diphenyl sulfonate 韶远科技(上海)有限公司 2024-12-13 CN claimed
CN-115974902-B 2-Cyano-1-phenyl vinyl boric acid pinacol ester and preparation method and application thereof 韶远科技(上海)有限公司 2024-10-18 CN claimed
CN-114702515-B Gold (III) complex and application thereof in cancer light therapy 中山大学 2023-08-01 CN claimed
EP-2445881-B1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM BOE TECHNOLOGY GROUP CO LTD (CN) 2017-11-15 EP claimed
US-8426601-B2 Process for making organic compounds and the organic compounds made therefrom GENERAL ELECTRIC COMPANY (US) 2013-04-23 US claimed
US-20120178938-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2012-07-12 US claimed
US-8178682-B2 Process for making organic compounds and the organic compounds made therefrom GENERAL ELECTRIC COMPANY (US) 2012-05-15 US claimed
EP-2445881-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM General Electric Company (US) 2012-05-02 EP claimed
US-20100331547-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2010-12-30 US claimed
WO-2010151389-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM GENERAL ELECTRIC COMPANY (US) 2010-12-29 WO claimed
EP-1768988-B1 NOVEL PHENYL-BORONIC ACID DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF GALDERMA RES & DEV (FR) 2009-01-28 EP claimed
CN-122055366-A GCN2 and PERK kinase modulators and methods of use thereof 德西费拉制药有限责任公司 2026-05-15 CN disclosed
US-20260103463-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-04-16 US disclosed
EP-4719606-A2 GCN2 AND PERK KINASE MODULATORS AND METHODS OF USE THEREOF Deciphera Pharmaceuticals, LLC (US) 2026-04-08 EP disclosed
US-12577254-B2 Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors Signal Rx Pharmaceuticals, Inc. 2026-03-17 US disclosed
WO-2002069970-A1 SUBSTITUTED 8-ARYLQUINOLINE PHOSPHODIESTERASE-4 INHIBITORS MERCK & CO., INC. (US) 2002-09-12 WO disclosed
US-20020103226-A1 Substituted 8-arylquinoline phosphodiesterase-4 inhibitors MERCK FROSST CANADA LTD. (CA) 2002-08-01 US disclosed
US-6410563-B1 RESPIRATORY SYSTEM DISORDERS; ANTIARTHRITIC AGENTS MERCK FROSST CANADA & CO. (CA) 2002-06-25 US disclosed
WO-2001046151-A1 SUBSTITUTED 8-ARYLQUINOLINE PHOSPHODIESTERASE-4 INHIBITORS MERCK FROSST CANADA & CO. (CA) 2001-06-28 WO disclosed
WO-2001032625-A1 ARYL- AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE AND SEROTONIN DU PONT PHARMACEUTICALS COMPANY (US) 2001-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100331547-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM CYP4F11, BCL6, CYP2F1 THRB 1008/4885ALDH1A1 2404/4885TSHR 682/4885
US-20020103226-A1 Substituted 8-arylquinoline phosphodiesterase-4 inhibitors PDE4A, PDE4B, PDE4C THRB 3314/4885ALDH1A1 384/4885TSHR 2928/4885
US-12577254-B2 Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors CHEK1, CDK1, CDK3 THRB 660/4885ALDH1A1 4453/4885TSHR 928/4885
US-20260103463-A1 PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT GLP1R, GPR119, GIPR THRB 56/4885ALDH1A1 2886/4885TSHR 61/4885
US-20120178938-A1 PROCESS FOR MAKING ORGANIC COMPOUNDS AND THE ORGANIC COMPOUNDS MADE THEREFROM CYP2F1, CYP4F2, CYP1B1 THRB 3142/4885ALDH1A1 583/4885TSHR 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.