Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748129 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2 | |
| SCHEMBL28396145 | 0.86 | FOLH1 (0.58) | ALDH1A1TYRFOLH1KMT2ATSHR | |
| SCHEMBL9750555 | 0.83 | ABCB1 (0.42) | ALDH1A1LMNATYRFOLH1SMN1; SMN2 | |
| SCHEMBL10449002 | 0.78 | BRS3 (0.46) | — | |
| SCHEMBL5609826 | 0.77 | ALDH1A1 (0.47) | ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2 | |
| SCHEMBL19291183 | 0.77 | PTPN1 (0.50) | ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2 | |
| SCHEMBL2125820 | 0.77 | ALDH1A1 (0.47) | ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2 | |
| SCHEMBL30628269 | 0.77 | ALDH1A1 (0.47) | ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2 | |
| SCHEMBL14476991 | 0.76 | LMNA (0.44) | ALDH1A1LMNATYRFOLH1KDM4E | |
| SCHEMBL14397902 | 0.76 | ALDH1A1 (0.46) | ALDH1A1LMNAFOLH1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |