Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420900 | 1.00 | CTSL (0.54) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL17351814 | 0.90 | CTSL (0.52) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL15937200 | 0.90 | CTSL (0.52) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL17275428 | 0.86 | CTSL (0.49) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL11573515 | 0.86 | CTSL (0.56) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL4399079 | 0.86 | CTSL (0.56) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL1132569 | 0.86 | CTSL (0.56) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL10421483 | 0.86 | CTSL (0.56) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL9656905 | 0.86 | CTSL (0.56) | CTSLCTSSMEN1LMNAKMT2A | |
| SCHEMBL9789291 | 0.86 | CTSL (0.56) | CTSLCTSSMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4939241-A | Diazo serines | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0285085-A2 | Amino acid derivatives, process for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |