SCHEMBL1132569

SCHEMBL1132569

C[C@@H](OCc1ccccc1)[C@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 4/20 0.56
CTSS P25774 4/20 0.56
ATM Q13315 1/20 0.54
CTSB P07858 3/20 0.54
MMP9 P14780 2/20 0.53
MMP8 P22894 2/20 0.53
CTSK P43235 4/20 0.53
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
KMT2A Q03164 1/20 0.52
CTRB1 P17538 2/20 0.51
ELANE P08246 1/20 0.51
ECE1 P42892 2/20 0.50
TRPM8 Q7Z2W7 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
RAB9A P51151 1/20 0.50
MME P08473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132567 1.00 CTSL (0.56) CTSLCTSSATMCTSBMMP9
SCHEMBL10421483 1.00 CTSL (0.56) CTSLCTSSATMCTSBMMP9
SCHEMBL11573515 1.00 CTSL (0.56) CTSLCTSSATMCTSBMMP9
SCHEMBL9417470 0.92 MMP9 (0.51) CTSLCTSSATMCTSBMMP9
SCHEMBL5196368 0.90 TRPM8 (0.58) CTSLCTSSATMCTSBMMP9
SCHEMBL12028840 0.89 CTSL (0.54) CTSLCTSSATMCTSBMMP9
SCHEMBL4399079 0.89 CTSL (0.56) CTSLCTSSATMCTSBCTSK
SCHEMBL9789291 0.89 CTSL (0.56) CTSLCTSSATMCTSBCTSK
SCHEMBL9656905 0.89 CTSL (0.56) CTSLCTSSATMCTSBCTSK
SCHEMBL6558624 0.89 CTSL (0.56) CTSLCTSSATMCTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
JP-53141240-A None JP disclosed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
CN-115053184-B Composition for forming EUV resist underlayer film 日产化学株式会社 2024-12-06 CN disclosed
EP-3988538-B1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO LTD (CN) 2024-08-07 EP disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP disclosed
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US disclosed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US disclosed
US-20220111056-A1 DRUG-LOADED EMULSION ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US disclosed
US-20170007709-A1 GLYCOAMINO ACID AND USE THEREOF AJINOMOTO CO., INC. (JP) 2017-01-12 US disclosed
US-8299035-B2 10a-azalide compound having 4-membered ring structure TAISHO PHARMACEUTUCAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20110152239-A1 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2011-06-23 US disclosed
EP-2287173-A1 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE Taisho Pharmaceutical Co., Ltd. (JP) 2011-02-23 EP disclosed
US-4939241-A Diazo serines FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1990-07-03 US disclosed
EP-0285085-A2 Amino acid derivatives, process for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-10-05 EP disclosed
US-4668683-A Cardiotonic quinazoline derivatives KYOWA HAKKO KOGYO K.K. (JP) 1987-05-26 US disclosed
JP-S53141240-A NOVEL THREONINE AND ALLOTHREONINE DERIVATIVES AND PREOCESS FOR THEIR PREPARATION TANABE SEIYAKU CO LTD 1978-12-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP CTSL 1366/4885CTSS 2330/4885ATM 970/4885
US-20220111056-A1 DRUG-LOADED EMULSION SLC43A1, SLC7A1, CETP CTSL 1794/4885CTSS 3871/4885ATM 3769/4885
US-20170007709-A1 GLYCOAMINO ACID AND USE THEREOF SLC6A15, NGLY1, SLC7A1 CTSL 2457/4885CTSS 3535/4885ATM 3216/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 CTSL 1811/4885CTSS 3839/4885ATM 3152/4885
US-20110152239-A1 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE ELOVL3, ELOVL5, SCD5 CTSL 3937/4885CTSS 4205/4885ATM 4860/4885
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ABCG2, CYP51A1, HACD3 CTSL 752/4885CTSS 1383/4885ATM 3641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.