Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382487 | 0.90 | REN (0.48) | REN | |
| SCHEMBL10421139 | 0.88 | REN (0.52) | REN | |
| SCHEMBL7305156 | 0.87 | REN (0.65) | REN | |
| SCHEMBL7332395 | 0.86 | REN (0.77) | REN | |
| SCHEMBL8909404 | 0.86 | REN (0.62) | REN | |
| SCHEMBL10421179 | 0.85 | REN (0.48) | REN | |
| SCHEMBL10422480 | 0.83 | REN (0.45) | REN | |
| SCHEMBL10422706 | 0.83 | REN (0.48) | REN | |
| SCHEMBL9555077 | 0.82 | REN (0.59) | REN | |
| SCHEMBL10422425 | 0.82 | REN (0.45) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904660-A | HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0281316-A2 | Renin inhibitors | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |