Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.56 |
| ▸ | PREP | P48147 | 2/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949889 | 1.00 | DPP4 (0.56) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL21430566 | 1.00 | DPP4 (0.56) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL23314867 | 0.84 | DPP4 (0.51) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL14609170 | 0.81 | DPP4 (0.41) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL4589694 | 0.81 | POLB (0.37) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL12324861 | 0.81 | DPP4 (0.41) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL14273591 | 0.81 | DPP4 (0.41) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL18519489 | 0.79 | DPP4 (0.36) | DPP4DPP8PREPFAPDPP9 | |
| SCHEMBL6389769 | 0.78 | ACE (0.41) | POLBL3MBTL1ACE | |
| SCHEMBL20038765 | 0.78 | EPHX1 (0.38) | DPP4PREPFAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4980343-A | Inhibit colon and rectal tumors | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | claimed |
| US-4980343-A | Inhibit colon and rectal tumors | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |