SCHEMBL18519489

SCHEMBL18519489

NCCOCC(=O)N1CCC[C@H]1C=O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 3/20 0.36
▸ DPP8 Q6V1X1 3/20 0.36
▸ FAP Q12884 2/20 0.36
▸ DPP9 Q86TI2 2/20 0.36
▸ PREP P48147 2/20 0.36
▸ SPHK1 Q9NYA1 1/20 0.33
▸ MVD P53602 2/20 0.33
▸ DPP7 Q9UHL4 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ POLB P06746 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16421615 0.79 MVD (0.41) DPP4SPHK1MVD
SCHEMBL12949889 0.79 DPP4 (0.56) DPP4DPP8FAPDPP9PREP
SCHEMBL21430566 0.79 DPP4 (0.56) DPP4DPP8FAPDPP9PREP
SCHEMBL10421372 0.79 DPP4 (0.56) DPP4DPP8FAPDPP9PREP
SCHEMBL19658205 0.76 SPHK1 (0.38) SPHK1POLBL3MBTL1
SCHEMBL25095633 0.74 STAT6 (0.36) DPP4DPP8FAPDPP9DPP7
SCHEMBL14273591 0.72 DPP4 (0.41) DPP4DPP8FAPDPP9PREP
SCHEMBL4589694 0.72 POLB (0.37) DPP4DPP8FAPDPP9PREP
SCHEMBL12324861 0.72 DPP4 (0.41) DPP4DPP8FAPDPP9PREP
SCHEMBL19696569 0.70 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9840537-B2 Selective delivery molecules and methods of use AVELAS BIOSCIENCES, INC. (US) 2017-12-12 — — US disclosed
US-20170044214-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE AVELAS ACQUISITION CORPORATION 2017-02-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044214-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE SLC7A1, SLC47A1, SLC47A2 DPP4 3161/4885DPP8 1778/4885FAP 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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