Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12324861 | 0.81 | DPP4 (0.41) | POLBL3MBTL1PREPDPP4FAP | |
| SCHEMBL14273591 | 0.81 | DPP4 (0.41) | POLBL3MBTL1PREPDPP4FAP | |
| SCHEMBL12949889 | 0.81 | DPP4 (0.56) | POLBL3MBTL1PREPDPP4FAP | |
| SCHEMBL10421372 | 0.81 | DPP4 (0.56) | POLBL3MBTL1PREPDPP4FAP | |
| SCHEMBL21430566 | 0.81 | DPP4 (0.56) | POLBL3MBTL1PREPDPP4FAP | |
| SCHEMBL20038765 | 0.78 | EPHX1 (0.38) | PREPDPP4FAP | |
| SCHEMBL6389769 | 0.78 | ACE (0.41) | POLBL3MBTL1ACE | |
| SCHEMBL11432958 | 0.78 | ACE (0.41) | POLBL3MBTL1ACE | |
| SCHEMBL14080195 | 0.78 | DPP4 (0.40) | POLBDPP4ACE | |
| SCHEMBL474931 | 0.78 | POLB (0.41) | POLBL3MBTL1PREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100621-A2 | TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | disclosed |