Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | PGC | P20142 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711346 | 0.93 | REN (0.32) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL10421584 | 0.82 | REN (0.48) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL9874806 | 0.79 | REN (0.47) | REN | |
| SCHEMBL9876291 | 0.79 | REN (0.47) | REN | |
| SCHEMBL9876598 | 0.79 | REN (0.52) | REN | |
| SCHEMBL10711360 | 0.78 | REN (0.40) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL9876341 | 0.78 | REN (0.54) | REN | |
| SCHEMBL9876330 | 0.76 | REN (0.45) | REN | |
| SCHEMBL9876262 | 0.76 | REN (0.45) | REN | |
| SCHEMBL10630739 | 0.76 | REN (0.45) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904660-A | HYPOTENSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |