Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | SOD1 | P00441 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421128 | 0.92 | PTGER4 (0.56) | PTPN1PTPN2PTPN6SOD1PTGER4 | |
| SCHEMBL10421199 | 0.82 | HMGB1 (0.48) | PTGER4HMGB1MRGPRX4 | |
| SCHEMBL10421183 | 0.82 | MRGPRX4 (0.55) | HMGB1MRGPRX4 | |
| SCHEMBL10697768 | 0.82 | MRGPRX4 (0.48) | HMGB1MRGPRX4AKR1C2AKR1C1 | |
| SCHEMBL1756444 | 0.81 | MRGPRX4 (0.63) | SOD1PTGER4PTGER1PTGER3PTGER2 | |
| SCHEMBL10420804 | 0.80 | HMGB1 (0.46) | SOD1PTGER4HMGB1MRGPRX4 | |
| SCHEMBL10420779 | 0.78 | MCL1 (0.47) | HMGB1MRGPRX4MCL1 | |
| SCHEMBL10422123 | 0.77 | HMGB1 (0.47) | HMGB1MRGPRX4MCL1 | |
| SCHEMBL10422132 | 0.77 | HMGB1 (0.43) | PTGER4HMGB1MRGPRX4 | |
| SCHEMBL1760344 | 0.76 | TP53 (0.56) | PTPN1PTGER4MRGPRX4MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918047-A | CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0253666-A2 | Heat-sensitive recording material containing dye-forming components | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |