Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422132 | 0.95 | HMGB1 (0.43) | HMGB1MRGPRX4RAB9ATP53PKM | |
| SCHEMBL10697768 | 0.89 | MRGPRX4 (0.48) | HMGB1MRGPRX4RAB9ATP53PKM | |
| SCHEMBL10420804 | 0.83 | HMGB1 (0.46) | HMGB1MRGPRX4RAB9ATP53PKM | |
| SCHEMBL10421183 | 0.83 | MRGPRX4 (0.55) | HMGB1MRGPRX4RAB9ATP53NPC1 | |
| SCHEMBL10422137 | 0.82 | PTPN1 (0.52) | HMGB1MRGPRX4PTGER4 | |
| SCHEMBL10422123 | 0.81 | HMGB1 (0.47) | HMGB1MRGPRX4KDM4EALDH1A1HPGD | |
| SCHEMBL28234304 | 0.80 | HMGB1 (0.57) | HMGB1MRGPRX4TP53HIF1AKDM4E | |
| SCHEMBL10421120 | 0.79 | SMN1; SMN2 (0.42) | HMGB1MRGPRX4SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL10420779 | 0.79 | MCL1 (0.47) | HMGB1MRGPRX4RAB9ATP53HIF1A | |
| SCHEMBL10421128 | 0.79 | PTGER4 (0.56) | HMGB1MRGPRX4RAB9AHIF1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918047-A | CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0253666-A2 | Heat-sensitive recording material containing dye-forming components | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |