Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10421199 | 0.89 | HMGB1 (0.48) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL10420804 | 0.86 | HMGB1 (0.46) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL10422123 | 0.84 | HMGB1 (0.47) | MRGPRX4HMGB1KDM4EALDH1A1HPGD | |
| SCHEMBL10422132 | 0.84 | HMGB1 (0.43) | MRGPRX4SMN1; SMN2TP53PKMNFKB1 | |
| SCHEMBL10421183 | 0.83 | MRGPRX4 (0.55) | MRGPRX4TP53HMGB1NPC1RAB9A | |
| SCHEMBL10421120 | 0.82 | SMN1; SMN2 (0.42) | MRGPRX4SMN1; SMN2HMGB1MEN1KMT2A | |
| SCHEMBL10422137 | 0.82 | PTPN1 (0.52) | MRGPRX4HMGB1AKR1C2AKR1C1 | |
| SCHEMBL10420809 | 0.80 | PPARA (0.50) | — | |
| SCHEMBL10420779 | 0.79 | MCL1 (0.47) | MRGPRX4TP53HMGB1NPC1RAB9A | |
| SCHEMBL10421128 | 0.79 | PTGER4 (0.56) | MRGPRX4HMGB1NPC1RAB9ARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253666-A2 | Heat-sensitive recording material containing dye-forming components | FUJI PHOTO FILM CO., LTD. (JP) | 1988-01-20 | — | — | EP | disclosed |