SCHEMBL10422239

SCHEMBL10422239

CC(NC(=O)CN)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)O)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 11/20 0.39
CTSD P07339 5/20 0.39
BMP1 P13497 1/20 0.39
CTSC P53634 1/20 0.39
FOLH1 Q04609 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422242 1.00 BACE1 (0.39) BACE1CTSDBMP1CTSCFOLH1
SCHEMBL31031496 0.92 CTSC (0.42) BMP1CTSCFOLH1
SCHEMBL30880105 0.90 ENPEP (0.45) BACE1CTSDBMP1
SCHEMBL10423777 0.88 BACE1 (0.44) BACE1CTSDFOLH1
SCHEMBL10423774 0.88 BACE1 (0.44) BACE1CTSDFOLH1
SCHEMBL29488080 0.86 FOLH1 (0.51) FOLH1
SCHEMBL30578645 0.86 FOLH1 (0.51) FOLH1
SCHEMBL29531660 0.86 NPSR1 (0.43) CTSC
SCHEMBL4968369 0.86 NPSR1 (0.43) CTSC
SCHEMBL4968366 0.86 NPSR1 (0.43) CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4933288-A DNA SEQUENCE ENCODING PROTEINS PROCESSABLE BY DIPHTHERIA TOXIN LEADERS CETUS CORPORATION (US) 1990-06-12 US claimed