SCHEMBL10422652

SCHEMBL10422652

CCCCCCCCCCCCCCC(CC)CCCCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.62
ALDH1A1 P00352 3/20 0.55
TDP1 Q9NUW8 1/20 0.55
OPRM1 P35372 1/20 0.52
TSHR P16473 2/20 0.52
CYP3A4 P08684 2/20 0.52
THRB P10828 1/20 0.50
CA2 P00918 2/20 0.48
DNM1 Q05193 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.43
PRSS1 P07477 1/20 0.43
PRSS2 P07478 1/20 0.43
PRSS3 P35030 1/20 0.43
GPR84 Q9NQS5 2/20 0.42
FDPS P14324 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18881158 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL996309 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL525160 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL19286610 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL7536480 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL20774446 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL5673275 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL7542521 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL22027598 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR
SCHEMBL11882565 1.00 LMNA (0.62) LMNAALDH1A1TDP1OPRM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4892680-A OXIDATION RESISTANCE NIPPON OIL CO., LTD. (JP) 1990-01-09 US disclosed