Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18881158 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL525160 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL19286610 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL7536480 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL20774446 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL5673275 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL10422652 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL7542521 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL22027598 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR | |
| SCHEMBL11882565 | 1.00 | LMNA (0.62) | LMNAALDH1A1TDP1OPRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-02-25 | — | — | US | disclosed |
| US-20200061056-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
| CN-109949870-A | A kind of molecular level base oil reconciliation optimization method | 杭州辛孚能源科技有限公司 | 2019-06-28 | — | — | CN | disclosed |
| US-20190167672-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| US-20180318294-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-11-08 | — | — | US | disclosed |
| US-20180092907-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-04-05 | — | — | US | disclosed |
| EP-2151233-B1 | TWO-COMPONENT OXIDATIVE HAIR DYE COMPOSITION | KAO CORP (JP) | 2017-08-09 | — | — | EP | disclosed |
| EP-2151232-B1 | OXIDATIVE HAIR DYE COMPOSITION | KAO CORP (JP) | 2017-04-12 | — | — | EP | disclosed |
| US-20170071933-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-03-16 | — | — | US | disclosed |
| US-20040156815-A1 | Hair cleansing composition | KAO CORPORATION (JP) | 2004-08-12 | — | — | US | disclosed |
| CN-1509698-A | Hair cosmetics | 花王株式会社 | 2004-07-07 | — | — | CN | disclosed |
| CN-1509700-A | Hair cleaner | 花王株式会社 | 2004-07-07 | — | — | CN | disclosed |
| CN-1509699-A | Hair cleaner | ������������ʽ���� | 2004-07-07 | — | — | CN | disclosed |
| EP-1433465-A2 | Hair cosmetic composition | Kao Corporation (JP) | 2004-06-30 | — | — | EP | disclosed |
| EP-1433464-A2 | Hair cleansing composition | Kao Corporation (JP) | 2004-06-30 | — | — | EP | disclosed |
| EP-1433466-A2 | Hair cleansing composition | Kao Corporation (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-20040115162-A1 | Dermatological preparations | KAO CORPORATION (JP) | 2004-06-17 | — | — | US | disclosed |
| US-6685953-B1 | WATER RETENTION CAPACITY; MOISTURIZER; ALKOXYALKYAMIDES OF ALKYLENEDICARBOXYLIC ACIDS | KAO CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
| EP-1166766-A1 | EXTERNAL PREPARATION COMPOSITIONS | Kao Corporation (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | LMNA 4438/4885ALDH1A1 1257/4885TDP1 4048/4885 |
| US-20170071933-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | LMNA 4438/4885ALDH1A1 1257/4885TDP1 4048/4885 |
| US-20180318294-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | LMNA 4438/4885ALDH1A1 1257/4885TDP1 4048/4885 |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, SULT2A1, CYP4Z1 | LMNA 4301/4885ALDH1A1 1445/4885TDP1 4353/4885 |
| US-20200061056-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | LMNA 4438/4885ALDH1A1 1257/4885TDP1 4048/4885 |
| US-20180092907-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | LMNA 4438/4885ALDH1A1 1257/4885TDP1 4048/4885 |
| US-20190167672-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | LMNA 4438/4885ALDH1A1 1257/4885TDP1 4048/4885 |
| US-20040156815-A1 | Hair cleansing composition | CUTA, TRPA1, SHH | LMNA 1497/4885ALDH1A1 2683/4885TDP1 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.