Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10334149 | 0.91 | KDM4E (0.75) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9832407 | 0.86 | KDM4E (0.81) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8310001 | 0.85 | KDM4E (0.67) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL16884170 | 0.84 | POLB (0.82) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11179651 | 0.83 | USP2 (0.69) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11400309 | 0.83 | SMN1; SMN2 (0.78) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11185330 | 0.82 | USP2 (0.67) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL13204390 | 0.82 | KDM4E (0.63) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL1889066 | 0.81 | KDM4E (0.67) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8308417 | 0.81 | KDM4E (0.67) | KDM4EMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212525-A1 | 5-SUBSTITUTED INDOLE 3-AMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | Origiant Pharmaceutical Co., Ltd (CN) | 2023-07-19 | — | — | EP | disclosed |