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Sugi Predict / Compounds / Chlorozotocin

Chlorozotocin

Chlorozotocin

SCHEMBL10424026

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nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.78
▸ KDM4E B2RXH2 1/20 0.78
▸ CYP2D6 P10635 1/20 0.78
▸ CYP2C19 P33261 1/20 0.78
▸ ADRA2A P08913 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ PDE4A P27815 1/20 0.41
▸ ADRA1A P35348 1/20 0.41
▸ HK2 P52789 5/20 0.38
▸ HK1 P19367 4/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ ABCB11 O95342 1/20 0.37
▸ GSR P00390 1/20 0.37
▸ TSHR P16473 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ PMP22 Q01453 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorozotocin SCHEMBL8539 0.93 LMNA (0.64) LMNAKDM4ECYP2D6CYP2C19ADRA2A
Chlorozotocin SCHEMBL1648834 0.93 LMNA (0.64) LMNAKDM4ECYP2D6CYP2C19ADRA2A
Chlorozotocin SCHEMBL11409480 0.93 LMNA (0.64) LMNAKDM4ECYP2D6CYP2C19ADRA2A
Chlorozotocin SCHEMBL11409484 0.93 LMNA (0.64) LMNAKDM4ECYP2D6CYP2C19ADRA2A
Streptozosin SCHEMBL22408645 0.93 LMNA (0.70) LMNAKDM4ECYP2D6CYP2C19ADRA2A
Chlorozotocin SCHEMBL19520816 0.92 LMNA (0.63) LMNAKDM4ECYP2D6CYP2C19ADRA2A
Streptozosin SCHEMBL121374 0.91 LMNA (0.64) LMNAKDM4ECYP2D6CYP2C19ADRA2A
Streptozosin SCHEMBL10201155 0.88 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19ALDH1A1
Streptozosin SCHEMBL4748 0.88 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19ALDH1A1
Streptozosin SCHEMBL18402588 0.88 LMNA (1.00) LMNAKDM4ECYP2D6CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4975421-A WATER SOLUBLE, IMPREGNATED IN A VEHICLE FOR TOPICAL APPLICATION; MICROBIOCIDES BIOGLUCAN, LP. (US) 1990-12-04 — — US disclosed