Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424761 | 0.87 | ALDH1A1 (0.58) | AKR1B1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10424513 | 0.87 | KMT2A (0.73) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL12177434 | 0.78 | ALDH1A1 (0.71) | FPR2AKR1B1SMN1; SMN2 | |
| SCHEMBL2607454 | 0.75 | ALDH1A1 (0.71) | AKR1B1KMT2AMAPTLMNAHTT | |
| SCHEMBL4877622 | 0.73 | SMN1; SMN2 (0.51) | FPR2MEN1KMT2AMAPTLMNA | |
| SCHEMBL22274780 | 0.73 | KMT2A (0.68) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL16007999 | 0.73 | FPR2 (1.00) | FPR2AKR1B1MEN1KMT2AMAPT | |
| SCHEMBL12177537 | 0.72 | MEN1 (0.58) | FPR2AKR1B1MEN1KMT2AMAPT | |
| SCHEMBL16922181 | 0.72 | NPC1 (0.66) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL2098194 | 0.72 | ALDH1A1 (0.59) | MEN1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927844-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-22 | — | — | US | disclosed |
| EP-0319712-A1 | N-substituted dichloromaleinimides | BAYER AG (DE) | 1989-06-14 | — | — | EP | disclosed |