Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | CASP7 | P55210 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425399 | 0.74 | CNR1 (0.46) | GBA1KDM4EMAPTHSD17B10GLA | |
| SCHEMBL10426487 | 0.72 | KDM4E (0.50) | KDM4EMAPTHSD17B10GLAGAA | |
| SCHEMBL10425402 | 0.68 | ADORA3 (0.47) | KDM4EMAPTHSD17B10GLAGAA | |
| SCHEMBL10425619 | 0.67 | PARP1 (0.49) | KDM4EMAPTHSD17B10GLAGAA | |
| SCHEMBL10425406 | 0.66 | CNR1 (0.74) | GBA1KDM4EMAPTHSD17B10GLA | |
| SCHEMBL28113320 | 0.66 | GBA1 (0.46) | GBA1KDM4EMAPTHSD17B10GLA | |
| SCHEMBL12325885 | 0.66 | KDM4E (0.59) | GBA1KDM4EMAPTHSD17B10GLA | |
| SCHEMBL28112757 | 0.66 | KDM4E (0.49) | GBA1KDM4EMAPTHSD17B10GAA | |
| SCHEMBL10425401 | 0.65 | CNR1 (0.60) | GBA1KDM4EMAPTHSD17B10GLA | |
| SCHEMBL10425400 | 0.64 | BACE1 (0.50) | KDM4EMAPTHSD17B10GLACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4897391-A | Tricyclic anti-allergy, antiinflammatory and anti-hyperproliferative compounds | SCHERING CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |