Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30449235 | 0.87 | TSHR (0.44) | HMGCRL3MBTL1PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL4570484 | 0.82 | TSHR (0.45) | L3MBTL1PABPC1APOBEC3AAPOBEC3GTSHR | |
| SCHEMBL30449085 | 0.81 | L3MBTL1 (0.39) | HMGCRL3MBTL1PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL13305477 | 0.76 | TSHR (0.41) | L3MBTL1PABPC1APOBEC3AAPOBEC3GTSHR | |
| SCHEMBL3342037 | 0.76 | TSHR (0.41) | L3MBTL1PABPC1APOBEC3AAPOBEC3GTSHR | |
| SCHEMBL31519148 | 0.75 | HMGCR (0.46) | HMGCRPPARGLMNAMAPT | |
| SCHEMBL9860197 | 0.75 | HMGCR (0.51) | HMGCRL3MBTL1PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL9860445 | 0.71 | HMGCR (0.58) | HMGCRL3MBTL1PPARGPPARAMAPT | |
| SCHEMBL9860442 | 0.71 | HMGCR (0.58) | HMGCRL3MBTL1PPARGPPARAMAPT | |
| SCHEMBL6037397 | 0.71 | TSHR (0.47) | HMGCRTSHRPPARGLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003624-A | — | — | None | — | — | JP | disclosed |
| JP-H023624-A | ACETYLENIC ESTER | MERCK & CO INC | 1990-01-09 | — | — | JP | disclosed |