Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10428516 | 0.89 | ALOX5 (0.67) | ALOX5PTGS1PTGS2CYP1A2CYP2D6 | |
| SCHEMBL10428318 | 0.88 | ALOX5 (0.65) | ALOX5PTGS1PTGS2HPGDSCNR2 | |
| SCHEMBL10428419 | 0.88 | ALOX5 (0.65) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10428416 | 0.87 | ALOX5 (0.68) | ALOX5PTGS1PTGS2LMNATSHR | |
| Hydrochloric Acid SCHEMBL10428671 | 0.87 | ALOX5 (0.64) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10428717 | 0.86 | PTGS1 (0.67) | ALOX5PTGS1PTGS2CYP1A2CYP2D6 | |
| SCHEMBL10428504 | 0.86 | ALOX5 (0.67) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| Prifelone SCHEMBL42678 | 0.85 | PTGS1 (1.00) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10428375 | 0.85 | ALOX5 (0.61) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10428299 | 0.84 | ALOX5 (0.75) | ALOX5PTGS1PTGS2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927835-A | ANTIPYRETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0331195-A2 | Acylphenol derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-09-06 | — | — | EP | disclosed |