Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.68 |
| ▸ | MAOA | P21397 | 9/20 | 0.62 |
| ▸ | MAOB | P27338 | 8/20 | 0.62 |
| ▸ | DRD3 | P35462 | 4/20 | 0.62 |
| ▸ | DRD4 | P21917 | 3/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.62 |
| ▸ | DRD1 | P21728 | 2/20 | 0.62 |
| ▸ | DRD5 | P21918 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HTR2C | P28335 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MLNR | O43193 | 1/20 | 0.62 |
| ▸ | HTR3B | O95264 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428487 | 0.94 | DRD2 (0.77) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL13532793 | 0.91 | DRD2 (0.82) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL10428496 | 0.90 | DRD2 (0.70) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL23097691 | 0.87 | DRD2 (0.67) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL11282280 | 0.86 | ADRA1D (0.70) | DRD2DRD3MAPTSLC6A2HRH2 | |
| SCHEMBL10428627 | 0.84 | DRD2 (0.76) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL23097618 | 0.84 | MEN1 (0.59) | DRD2MAOADRD3DRD4HTR1A | |
| SCHEMBL10571607 | 0.84 | DRD2 (0.94) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL10428566 | 0.84 | DRD2 (0.75) | DRD2MAOAMAOBDRD3DRD4 | |
| SCHEMBL10428737 | 0.84 | DRD2 (0.81) | DRD2MAOAMAOBDRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914094-A | CARBOSTYRIC OR BENZOXAZINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0226441-A2 | Preparation of pharmaceutical compositions for the treatment of hypoxia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |