Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | SI | P14410 | 3/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957750 | 0.87 | MGAM (0.53) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL4957753 | 0.87 | MGAM (0.53) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL19911566 | 0.85 | MGAM (0.52) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL19911551 | 0.82 | MGAM (0.49) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL27627284 | 0.78 | ALDH1A1 (0.46) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL10428731 | 0.76 | KCNMA1 (0.61) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL6818351 | 0.76 | MGAM (0.44) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL19911542 | 0.75 | MAPT (0.47) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL8424662 | 0.75 | ALDH1A1 (0.46) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL210082 | 0.75 | NSD2 (0.61) | NSD2ALDH1A1TXNRD1TXNRD3TXNRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942248-A | CARBAMYLATION OF AMINO ACIDS BY REACTION WITH TERT-ALKYL ESTER A OF 1H-BENZOTRIAZOLE-1-CARBOXYLIC ACID TO FOR BLOCKED AMINO GROUP | PPG INDUSTRIES, INC. (US) | 1990-07-17 | — | — | US | disclosed |