Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570148 | 0.89 | DRD2 (0.59) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL10568577 | 0.88 | DRD2 (0.51) | DRD2DRD4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL10569016 | 0.88 | DRD2 (0.58) | DRD2DRD4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL10569951 | 0.88 | DRD2 (0.58) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL10569948 | 0.87 | DRD2 (0.54) | DRD2KCNH2DRD4DRD3HTR1A | |
| SCHEMBL10570868 | 0.85 | DRD2 (0.56) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL10570576 | 0.85 | HTR1A (0.48) | DRD2KCNH2DRD4DRD3HTR1A | |
| SCHEMBL10571702 | 0.85 | DRD2 (0.54) | DRD2DRD4DRD3 | |
| SCHEMBL10576246 | 0.84 | DRD2 (0.53) | DRD2KCNH2DRD4DRD3HTR1A | |
| SCHEMBL10570129 | 0.83 | DRD2 (0.55) | DRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914094-A | CARBOSTYRIC OR BENZOXAZINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0226441-A2 | Preparation of pharmaceutical compositions for the treatment of hypoxia | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |