Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | EDNRA | P25101 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429040 | 0.82 | KMT2A (0.42) | KMT2AMEN1EDNRAHPGDMAPK9 | |
| SCHEMBL10429089 | 0.81 | CYP3A4 (0.41) | KMT2AMEN1EDNRAHPGDMAPK9 | |
| SCHEMBL10428927 | 0.81 | EDNRA (0.55) | KMT2AMEN1EDNRAHPGDALDH1A1 | |
| SCHEMBL805660 | 0.76 | EDNRA (0.55) | KMT2AMEN1EDNRAHPGDKDM4E | |
| SCHEMBL14907918 | 0.74 | MEN1 (0.51) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10428886 | 0.74 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10428870 | 0.74 | ALDH1A1 (0.41) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22404286 | 0.74 | EDNRA (0.56) | KMT2AMEN1EDNRAHPGDKDM4E | |
| SCHEMBL10428878 | 0.73 | MEN1 (0.61) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL10428914 | 0.73 | TDP1 (0.40) | KDM4EALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929741-A | ANTISECRETORY AGENTS, GASTRIC JUICE, ANTIULCER AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-29 | — | — | US | disclosed |