Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | EDNRA | P25101 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428889 | 0.82 | KMT2A (0.47) | KMT2AMEN1HPGDEDNRAKDM4E | |
| SCHEMBL10429089 | 0.79 | CYP3A4 (0.41) | KMT2AMEN1HPGDEDNRAHTT | |
| SCHEMBL10428927 | 0.79 | EDNRA (0.55) | KMT2AMEN1HPGDEDNRAALDH1A1 | |
| SCHEMBL10428869 | 0.79 | HPGD (0.51) | KMT2AMEN1HPGDALDH1A1HTT | |
| SCHEMBL10428875 | 0.78 | FFAR1 (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL10428845 | 0.74 | DHFR (0.42) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9155961 | 0.72 | CYP3A4 (0.47) | KMT2AMEN1HPGDEDNRAKDM4E | |
| SCHEMBL805660 | 0.68 | EDNRA (0.55) | KMT2AMEN1HPGDEDNRAKDM4E | |
| SCHEMBL22404286 | 0.66 | EDNRA (0.56) | KMT2AMEN1HPGDEDNRAKDM4E | |
| SCHEMBL16437028 | 0.66 | TSHR (0.39) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929741-A | ANTISECRETORY AGENTS, GASTRIC JUICE, ANTIULCER AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1990-05-29 | — | — | US | disclosed |