Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662024 | 1.00 | MAPT (0.50) | MAPTLMNAMEN1KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL27672121 | 0.98 | MAPT (0.49) | MAPTLMNAMEN1KMT2AALOX15 | |
| SCHEMBL2494933 | 0.76 | LMNA (0.79) | MAPTLMNACYP3A4AMY1AALDH1A1 | |
| SCHEMBL2494935 | 0.76 | LMNA (0.79) | MAPTLMNACYP3A4AMY1AALDH1A1 | |
| SCHEMBL11242364 | 0.70 | CYP3A4 (0.38) | MAPTLMNAMEN1KMT2AALOX15 | |
| SCHEMBL9661029 | 0.68 | CYP1A2 (0.69) | MAPTLMNAMEN1KMT2AALOX15 | |
| SCHEMBL9661025 | 0.68 | CYP1A2 (0.69) | MAPTLMNAMEN1KMT2AALOX15 | |
| SCHEMBL28002652 | 0.68 | CYP3A4 (0.42) | MAPTLMNAMEN1KMT2AALOX15 | |
| SCHEMBL11563938 | 0.68 | CYP3A4 (0.42) | MAPTLMNAMEN1KMT2AALOX15 | |
| SCHEMBL10429289 | 0.68 | MEN1 (0.50) | MAPTLMNAMEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908363-A | Antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1990-03-13 | — | — | US | disclosed |