SCHEMBL11242364

SCHEMBL11242364

C(=NOn1ccnc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
PLA2G7 Q13093 1/20 0.37
ALOX15 P16050 2/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
TBXAS1 P24557 3/20 0.35
CYP11B1 P15538 3/20 0.35
CYP11B2 P19099 3/20 0.35
CYP19A1 P11511 2/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
QPCT Q16769 1/20 0.35
CYP4Z1 Q86W10 1/20 0.35
QPCTL Q9NXS2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11238042 0.84 AMY1A (0.42) LMNAL3MBTL1TBXAS1CYP11B1CYP11B2
SCHEMBL9662024 0.70 MAPT (0.50) CYP3A4ALOX15LMNAL3MBTL1POLB
SCHEMBL10429281 0.70 MAPT (0.50) CYP3A4ALOX15LMNAL3MBTL1POLB
Hydrochloric Acid SCHEMBL27672121 0.69 MAPT (0.49) CYP3A4ALOX15LMNAL3MBTL1POLB
SCHEMBL3817790 0.67 TBXAS1 (0.47) CYP3A4ALOX15LMNATBXAS1CYP11B1
SCHEMBL11225677 0.67 NFKB1 (0.31) TBXAS1QPCTQPCTL
SCHEMBL28790617 0.66 PPARG (0.47) LMNAALDH1A1CYP24A1KMT2A
SCHEMBL9709937 0.65 LMNA (0.57) PLA2G7LMNAL3MBTL1TAAR1MAPT
SCHEMBL27671484 0.64 PARL (0.46) CYP3A4MAPTALDH1A1HPGDMEN1
SCHEMBL12018747 0.64 LMNA (0.50) PLA2G7LMNAL3MBTL1TAAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed