Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255796 | 0.83 | ABL1 (0.59) | MAPTSYKCDK2MAPK1MAOB | |
| SCHEMBL4544836 | 0.81 | KMT2A (0.66) | MAPTGAASYKKMT2AALDH1A1 | |
| SCHEMBL8526184 | 0.81 | NFKB1 (0.69) | MAPTGAASYKHDAC3HDAC1 | |
| SCHEMBL9506899 | 0.79 | POLB (0.49) | MAPTGAAHDAC3HDAC1HDAC2 | |
| SCHEMBL9505971 | 0.79 | MEN1 (0.55) | MAPTGAAKMT2AALDH1A1MEN1 | |
| SCHEMBL11291398 | 0.79 | SYK (0.59) | MAPTGAASYKHDAC3HDAC1 | |
| SCHEMBL14869861 | 0.79 | MAPT (0.62) | MAPTGAASYKKMT2AALDH1A1 | |
| SCHEMBL3957572 | 0.79 | MAPT (0.58) | MAPTGAASYKKMT2AALDH1A1 | |
| SCHEMBL4544826 | 0.77 | NFKB1 (0.73) | MAPTGAASYKKMT2AALDH1A1 | |
| SCHEMBL4544792 | 0.77 | NFKB1 (0.73) | MAPTGAASYKKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4942225-A | Preparation of diazo and azo compounds using azidoformamidium salts | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |