Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949605 | 0.82 | KDM4E (0.33) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL3949607 | 0.82 | KDM4E (0.33) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL10429526 | 0.81 | NR1I2 (0.32) | NR1I2PGRPTGS2 | |
| SCHEMBL8669676 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL11130790 | 0.75 | NR1I2 (0.32) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL4048933 | 0.75 | KDM4E (0.30) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL4048939 | 0.75 | KDM4E (0.30) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL11497574 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL3188369 | 0.68 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL1387526 | 0.68 | KDM4E (0.34) | KDM4EALDH1A1CYP3A4MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382411-A2 | Delivery of cytotoxic agents | ELI LILLY AND COMPANY (US) | 1990-08-16 | — | — | EP | disclosed |